Description
MOTS-c 40mg – Mitochondrial Research Peptide
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a naturally occurring 16-amino acid peptide encoded within mitochondrial DNA. Unlike most peptides encoded by nuclear DNA, MOTS-c originates from the mitochondrial genome and functions as a signaling molecule involved in regulating cellular metabolism, energy homeostasis, and adaptive stress responses.
Scientific research has demonstrated that MOTS-c participates in communication between mitochondria and the nucleus, influencing metabolic pathways associated with glucose utilization, lipid metabolism, insulin sensitivity, and mitochondrial function. Investigators continue to study its interactions with AMP-activated protein kinase (AMPK), oxidative stress pathways, and mechanisms that regulate cellular adaptation during metabolic stress and exercise.
Cellular Genix Labs manufactures MOTS-c 40mg using advanced peptide synthesis and rigorous quality-control procedures to provide a reliable research-grade peptide for reproducible laboratory investigations.
Research Applications
Researchers investigate MOTS-c in studies involving:
- Mitochondrial signaling
- Cellular energy metabolism
- AMPK activation
- Glucose metabolism
- Insulin signaling pathways
- Lipid metabolism
- Mitochondrial biogenesis
- Oxidative stress responses
- Exercise physiology
- Cellular stress adaptation
- Healthy aging and longevity research
- Skeletal muscle metabolism
- Metabolic flexibility
- Endocrine signaling
Product Specifications
- Compound: MOTS-c
- Quantity: 40mg
- Purity: ≥99% (HPLC/MS Verified)
- Sequence Length: 16 amino acids
- Appearance: White to off-white lyophilized powder
- Form: Lyophilized peptide
- Grade: Research Grade
- Storage: Store refrigerated at 2–8°C. For long-term storage, keep frozen at −20°C. Protect from light, moisture, and repeated freeze-thaw cycles.
Scientific Background
MOTS-c is one of the first mitochondrial-derived peptides identified as a regulator of metabolic homeostasis. Research has demonstrated that it functions as a mitochondrial signaling molecule capable of influencing nuclear gene expression during periods of metabolic stress.
Experimental investigations continue to explore MOTS-c’s role in:
- Mitochondrial-to-nuclear communication
- AMPK-mediated metabolic signaling
- Glucose utilization
- Fatty acid oxidation
- Exercise adaptation
- Skeletal muscle physiology
- Mitochondrial quality control
- Oxidative stress regulation
- Cellular resilience
- Healthy aging research
Because of its unique mitochondrial origin, MOTS-c has become an important research tool for scientists studying metabolism, exercise physiology, and age-related cellular function.
Research Use Only
This product is supplied exclusively for laboratory research conducted by qualified professionals.
It is not intended for human or veterinary use, diagnosis, treatment, cure, or prevention of any disease. Statements regarding this product have not been evaluated by the U.S. Food and Drug Administration. Products sold by Cellular Genix Labs are intended solely for lawful laboratory research.






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