Description

FOXO4-DRI 10mg – Senolytic Research Peptide

FOXO4-DRI is a synthetic D-retro-inverso peptide engineered to disrupt the interaction between Forkhead Box O4 (FOXO4) and the tumor suppressor protein p53. In preclinical research, this interaction has been investigated because it contributes to the survival of senescent cells—cells that have permanently stopped dividing but remain metabolically active. Disrupting the FOXO4-p53 interaction has been shown in experimental models to selectively induce apoptosis in senescent cells while largely sparing healthy cells.

FOXO4-DRI has become an important research tool in the rapidly growing field of senolytics, where investigators study the biological effects of reducing senescent cell burden. Ongoing laboratory research explores its role in aging biology, tissue regeneration, inflammation, cellular stress responses, and age-related physiological decline. Current evidence is primarily limited to cell culture and animal studies; human efficacy and safety have not been established.

Cellular Genix Labs manufactures FOXO4-DRI 10mg using advanced peptide synthesis and rigorous quality-control procedures to provide consistent purity and reproducibility for laboratory investigations.

Research Applications

Researchers investigate FOXO4-DRI in studies involving:

• Cellular senescence
• Senolytic research
• FOXO4-p53 signaling
• Programmed cell death (apoptosis)
• Healthy aging biology
• Tissue regeneration models
• Cellular stress responses
• DNA damage signaling
• Inflammatory signaling pathways
• Longevity research
• Cellular homeostasis
• Molecular gerontology

Product Specifications

• Compound: FOXO4-DRI
• Quantity: 10mg
• Purity: ≥99% (HPLC/MS Verified)
• Appearance: White to off-white lyophilized powder
• Form: D-retro-inverso peptide
• Grade: Research Grade
• Storage: Store refrigerated at 2–8°C. For long-term storage, keep frozen at −20°C. Protect from moisture, light, and repeated freeze-thaw cycles
  

  Scientific Background

  FOXO4-DRI was developed to investigate mechanisms that regulate senescent cell survival. In preclinical studies, disrupting the FOXO4-p53 interaction has been associated with selective removal of senescent cells, making the peptide a widely studied tool in senolytic research. Investigators continue to explore its potential effects on tissue function, inflammation, stem cell biology, and age-associated cellular changes. While these findings have generated significant scientific interest, they remain investigational and should not be interpreted as established clinical outcomes.

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  Research Use Only

  This product is supplied exclusively for laboratory research conducted by qualified professionals.

  It is not intended for human or veterinary use, diagnosis, treatment, cure, or prevention of any disease. Statements regarding this product have not been evaluated by the U.S. Food and Drug Administration. Products sold by Cellular Genix Labs are intended solely for lawful laboratory research.